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Locke can speak interestingly to the problem of transitional justice, that is, how to deal withthose who committed human rights abuses under authoritarian regimes once those regimes democratize. The essay focuses mainly on the "hard case" of transitional justice, in which former members of an authoritarian regime retain significant capacity for violence, and so the ability to threaten the new polity if attempts are made to punish them. Locke's law of nature suggests that human rights abusers should be punished, although not at the expense of social stability.But it also grounds the apparently un-Lockean claims, consistent with some of Locke's occasional writings, that abusersquaeschewers of reason may be treated as beasts that do not enjoy natural rights, and that little account need be taken of the victims of such abusers. Using Locke's thought in this way both illuminates it and clarifies what is at stake in the debate about transitional justice.

To access publisher full text version of this article. Please click on the hyperlink in Additional Links field ; We report a prostate cancer genome-wide association follow-on study. We discovered four variants associated with susceptibility to prostate cancer in several European populations: rs10934853[A] (OR = 1.12, P = 2.9 x 10(-10)) on 3q21.3; two moderately correlated (r2 = 0.07) variants, rs16902094[G] (OR = 1.21, P = 6.2 x 10(-15)) and rs445114[T] (OR = 1.14, P = 4.7 x 10(-10)), on 8q24.21; and rs8102476[C] (OR = 1.12, P = 1.6 x 10(-11)) on 19q13.2. We also refined a previous association signal on 11q13 with the SNP rs11228565[A] (OR = 1.23, P = 6.7 x 10(-12)). In a multivariate analysis using 22 prostate cancer risk variants typed in the Icelandic population, we estimated that carriers in the top 1.3% of the risk distribution are at a 2.5 times greater risk of developing the disease than members of the general population. ; info:eu-repo/grantAgreement/EC/FP7/218071 European Union 202059 V Foundation US Department of Veterans Affairs Academy of Finland Sigrid Juselius Foundation Pirkanmaa Hospital District, Tampere University Hospital